NCS Clinical Trials

NCS Clinical Trials

At Northwest Cancer Specialists we sponsor more clinical trials than any other cancer treatment facility in the Portland-Vancouver area.

ASCO Cancer Foundation

NCS won the prestigious American Cancer Society of Clinical Oncology (ASCO) Clinical Trial Participation Award in 2007.

Please see below for more information on our open trials.

Breast

Randomized Trial of Fulvestrant With or Without Dasatinib in Men and Postmenopausal Women Who Have Hormone Receptor-Positive Advanced Breast Cancer Previously Treated With an Aromatase Inhibitor (Study #06030)

BETH Study: Treatment of HER2 Positive Breast Cancer With Chemotherapy Plus Trastuzumab vs Chemotherapy Plus Trastuzumab Plus Bevacizumab (Study #07119)

A Clinical Trial Comparing the Combination of TC Plus Bevacizumab to TC Alone and to TAC for Women With Node-Positive or High-Risk Node-Negative, HER2-Negative Breast Cancer (Study #07132)

A Phase 2 Study of EZN-2208 in Patients With Metastatic Breast Cancer (PEG-SN38) (Study #07142)

A Study Comparing Eribulin Mesylate and Ixabepilone in Causing or Exacerbating Neuropathy in Patients With Advanced Breast Cancer (Study #08077)

Efficacy and Safety Evaluating IPI-504 With Trastuzumab in Patients With Pretreated, Locally Advanced or Metastatic HER2 Positive Breast Cancer (Study #08180)

Study Evaluating Neratinib vs Lapatinib Plus Capecitabine for ErbB2 Positive Advanced Breast Cancer (Study #08200)

Study Evaluating the Effects of Neratinib in Women With Early Stage Breast Cancer (ExteNET) (Study #08201)

Everolimus in Combination With Trastuzumab and Paclitaxel in the Treatment of HER2 Positive Locally Advanced or Metastatic Breast Cancer (BOLERO-1) (Study #08217)

Daily Everolimus in Combination With Trastuzumab and Vinorelbine in HER2/Neu Positive Women With Locally Advanced or Metastatic Breast Cancer (BOLERO-3) (Study #08223)

GI Malignancies

Docetaxel+Oxali+/-Cetux Met Gastric/GEJ (Study #06063)

PEAK: A Phase 2 Study of Panitumumab Plus mFOLFOX6 vs. Bevacizumab Plus mFOLFOX6 for First Line Treatment of Metastatic Colorectal Cancer Subjects With Wild-Type KRAS Tumors (Study #08113)

GU Malignancies

Global Investigation of Therapeutic Decisions in Hepatocellular Carcinoma and of Its Treatment With Sorafenib (GIDEON) (Study #08142)

Gynecologic Malignancies

Platinum Resistant Ovarian Cancer Evaluation of Doxil and EC14 Combination Therapy  (Study #08099)

BIBF 1120 or Placebo in Combination With Paclitaxel and Carboplatin in First Line Treatment of Ovarian Cancer (Study #08194)

Efficacy and Safety of MORAb-003 in Subjects With Platinum-sensitive Ovarian Cancer in First Relapse (Study #09091)

Hematologic Malignancies

PRELUDE:Study to Investigate the Prevention of Relapse in Lymphoma Using Daily Enzastaurin (Study #05007) 

Study of Bendamustine Hydrochloride and Rituximab (BR) Compared With R-CVP or R-CHOP in the First-Line Treatment of Patients With Advanced Indolent Non-Hodgkin's Lymphoma (NHL) or Mantle Cell Lymphoma (MCL) (Study #07152)

Ofatumumab + Chlorambucil vs. Chlorambucil Monotherapy in Previously Untreated Patients With Chronic Lymphocytic Leukemia (COMPLEMENT 1) (Study #08074)

Safety and Efficacy of RAD001 in Patients With Mantle Cell Lymphoma Who Are Refractory or Intolerant to Velcade® Therapy. (PILLAR-1) (Study #08087)

Study of the Safety and Tolerability of PCI-32765 in Patients With Recurrent B Cell Lymphoma (PCYC-04753) (Study #09039)

Lung

RADIANT: A Study of Tarceva After Surgery With or Without Adjuvant Chemotherapy in NSCLC Patients Who Have EGFR-Positive Tumors (Adjuvent) (Study #06026)

Sunitinib Non Small Cell Lung Cancer Patients Over 70 (Study #06135)

Oral HYCAMTIN Plus Whole Brain Radiation Therapy In Treatment Of Brain Metastases Resulting From Non-Small Lung Cancer (Study #07155)

Anemia Treatment for Advanced NSCLC Patients Receiving Chemotherapy (Study #08035)

A Study of Pemetrexed, Carboplatin and Bevacizumab in Patients With Nonsquamous Non-Small Cell Lung Cancer (Study #08044)

A Study of ASA404 or Placebo in Combination With Docetaxel in Second-Line Treatment for (Stage IIIb/IV) Non-Small Cell Lung Cancer (Study #08094)

A Study of Advanced or Metastatic Non-small Cell Lung Cancer (Study #09078) 

Multiple Myelomas

Randomized Phase 3b Study in Previously Untreated Multiple Myeloma Patients: VELCADE,Thalidomide, and Dexamethasone Versus VELCADE and Dexamethasone Versus VELCADE, Melphalan, and Prednisone (UPFRONT) (Study #06108)

A Study of the Safety and Pharmacology of SGN-40 Administered in Combination With Bortezomib in Patients With Relapsed or Refractory Multiple Myeloma (Study #09013)

Study to Assess the Effectiveness of RCHOP With or Without VELCADE in Previously Untreated Non-Germinal Center B-Cell-like Diffuse Large B-Cell Lymphoma Patients (Study #09064)

Translational Oncology

Study of CGC-11047 When Used in Individual Combinations With 1) Gemcitabine or 2) Docetaxel or 3) Bevacizumab or 4) Erlotinib or 5) Cisplatin or 6) 5-Flurouracil or 7) Sunitinib in Patients With Advanced Solid Tumors or Lymphoma  (Study #05033)

Study of XL184 in Adults With Advanced Malignancies (Study #09101)

Safety & Pharmacokinetics Study Of Azacitidine (SC And Oral) In Subjects With MDS, CMML, AML, Lymphoma And Multiple Myeloma (RACE) (Study # 08061)

Study to Evaluate Safety and Effectiveness of Lenalidomide in Combination With Docetaxel and Prednisone for Patients With Castrate-Resistant Prostate Cancer (Mainsail) (Study # 09073)